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Altoona (4-2) at Bishop McDevitt (5-1), 7
Notable: The Crusaders are a pass-first team, and QB Sebastian Williams has thrown for 1,387 yards this year.
Bedford (2-4) at Somerset (0-6), 7
Notable: The Bisons scored 20 points in a game for the first time this season in last week's 22-13 win.
Central Cambria (5-1) at Forest Hills (2-4), 7
Notable: Despite being 5-1, Red Devils are current No. 3 seed in D6 3A. Forest Hills at 2-4 is No. 2 in 4A.
Penn Cambria (4-2) at Chestnut Ridge (2-4), 7
Notable: Lions last beat Panthers in 2021, but Penn Cambria has won the last four by combined 130-43.
Penns Valley (1-5) at Central (5-1), 7
Notable: Despite having a loss and Cambria Heights being unbeaten, Central is just 10 points back of the first seed.
Philipsburg-Osceola (4-2) at Bellefonte (3-3), 7
Notable: Red Raiders, top seed in D6 4A, have won 11 of the past 12 meetings against Philipsburg-Osceola.
Tyrone (3-3) at Huntingdon (2-4), 7
Notable: Eagles won regular-season matchup last year, but the Bearcats eliminated Tyrone in playoffs.
Berlin Brothersvalley (5-1) at Tussey Mountain (0-6), 7
Notable: Berlin Brothersvalley's Carter Durst has rushed for 524 yards and eight touchdowns this season.
Claysburg-Kimmel (0-6) at Glendale (2-4), 7
Notable: C-K is 4-0 against the Vikings the last two seasons and have eliminated them both years in the playoffs.
Everett (0-6) at Windber (5-2), 7
Notable: Warriors last win was 7-6 over Windber Oct. 3, 2025. They have lost 10 straight since.
Meyersdale (5-1) at Northern Bedford (3-3), 7
Notable: Junior Caleb Sines has rushed for 756 yards and six touchdowns for Meyersdale this year.
Moshannon Valley (4-2) at Curwensville (0-6), 7
Notable: The Golden Tide have allowed at least 41 points in four of their six losses this season.
Mount Union (6-0) at Juniata Valley (4-2), 7
Notable: Juniata Valley's win last week moved the Hornets to No. 3 in D6 Class 1A. Trojans are third in 2A.
Cambria Heights (6-0) at Portage (3-3), 7
Notable: Mustangs haven't beaten Highlanders in Heritage play (0-4) and have been outscored 134-12.
Northern Cambria (3-3) at Marion Center (4-2), 7
Notable: Colts are currently the No. 7 ranked team in the eight-team District 6 Class 1A playoff field.
SATURDAY
Bellwood-Antis (5-1) at Bishop Guilfoyle (5-1), 7
Notable: BG's only loss is to District 6 Class 2A top-ranked Richland. Bellwood-Antis is ranked No. 2.