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Chambersburg (1-4) at Altoona (3-2), 7
Notable: Chambersburg snapped a five-game series losing streak to Altoona last year in a 28-10 win.
Bishop Guilfoyle (4-1) at Tyrone (3-2), 7
Notable: With its loss to Bellwood-Antis last week, Tyrone is currently outside the 3A playoff field.
Chestnut Ridge (2-3) at Central Cambria (4-1), 7
Notable: Red Devils have not won more than four games since 2014 when they finished 5-5.
Forest Hills (2-3) at Bedford (1-4), 7
Notable: At 2-3, Rangers are current No. 2 seed in District 6 Class 4A, just behind Bellefonte.
Huntingdon (2-3) at Central (4-1), 7
Notable: A Central win would do wonders for Dragons' playoff hopes and basically end Bearcats' shot.
Penn Cambria (3-2) at Westmont Hilltop (2-3), 7
Notable: Panthers are also now currently on the outside of the District 6 Class 3A playoff field.
Philipsburg-Osceola (4-1) at Bellwood-Antis (4-1), 7
Notable: Blue Devils had not lost to P-O since 2007 before a 31-28 Mountaineers win last season.
Glendale (2-3) at Mount Union (5-0), 7
Notable: Through five games, Mount Union's Nasir Collins has 775 yards and 19 touchdowns rushing.
Juniata Valley (3-2) at Moshannon Valley (4-1), 7
Notable: Green Hornets have won six of the last seven meetings, but Mo Valley won 38-21 in 2024.
North Star (4-1) at Everett (0-5), 7
Notable: Neither team played last week. North Star won by forfeit, and Everett has forfeited two in a row.
Northern Bedford (2-3) at Tussey Mountain (0-5), 7
Notable: Titans scored 13 points last week against Meyersdale, doubling their season total.
Southern Huntingdon (3-2) at Claysburg-Kimmel (0-5), 7
Notable: Rockets are trying to win their fourth game for the first time since going 7-4 in 2022.
Conemaugh Valley (0-5) at Cambria Heights (5-0), 7
Notable: Jays have been outscored 237-46. Heights has outscored opponents, 172-49.
Northern Cambria (2-3) at West Shamokin (1-4), 7
Notable: Since the Wolves joined the Heritage, Colts have not lost on the field to them (forfeit in '21).
Penns Manor (1-4) at Portage (2-3), 7
Notable: Comets have won four of the last five meetings including last year's 21-20 triumph.
Butler (3-2) at Hollidaysburg (3-2), 7
Notable: Teams meeting for the fifth year in a row, and the Golden Tigers have won the last three.