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Texans 30, Bengals 27
CINCINNATI -- C.J. Stroud directed a last-minute, game-winning drive for the second straight week, finishing with 356 yards passing and leading the Houston Texans to a victory over the Cincinnati Bengals.
With the game tied at 27-all and 1:33 remaining, Stroud moved the Texans 55 yards in six plays to set up a 38-yard field goal by Matt Ammendola as time expired.
Noah Brown had 172 yards receiving for the Texans and Devin Singletary ran for 150 yards and a score. Joe Burrow threw for 357 yards and two touchdowns for the Bengals but was intercepted twice in the fourth quarter.
Browns 33, Ravens 31
BALTIMORE -- Dustin Hopkins kicked a 40-yard field goal as time expired to cap a furious Cleveland rally in the fourth quarter, and the Browns edged the Baltimore Ravens. Cleveland trailed 31-17 before Deshaun Watson delivered the type of victory the Browns have been waiting for from their high-priced quarterback.
Watson threw a 10-yard touchdown pass to Elijah Moore with 8:57 remaining. Then one of Lamar Jackson's passes caromed high into the air and was picked off by Greg Newsome II, and he returned the interception 34 yards for a TD just 41 seconds later.
Vikings 27, Saints 19
MINNEAPOLIS -- Joshua Dobbs threw for a career-high 268 yards and contributed two touchdowns in his first start for Minnesota as the Vikings held on to beat the New Orleans Saints for their fifth straight victory.
The Vikings built a 24-point halftime lead and improved to 6-4. T.J. Hockenson outgained the Saints by himself in the first half with 10 catches for 128 yards and a score.
Colts 10, Patriots 6
FRANKFURT, Germany -- Jonathan Taylor ran for a first-quarter touchdown and Mac Jones threw a crucial interception in the fourth quarter and the Indianapolis Colts held on for a win over New England Patriots in Germany.
Jones was sacked five times in the first half and was replaced with backup Bailey Zappe late in the fourth quarter. Trailing 10-6, Jones drove the Patriots inside the red zone but was intercepted by Julian Blackmon on a pass intended for Mike Gesicki at the 1-yard line.
49ers 34, Jaguars 3
JACKSONVILLE, Fla. -- Brock Purdy threw three touchdown passes, including a 66-yarder to George Kittle, and the San Francisco 49ers seemingly fixed all their woes with a cross-country trip and a drubbing of Jacksonville that ended a three-game skid.
Deebo Samuel returned from a three-game absence and added a 23-yard scoring run for the 49ers, who stopped Jacksonville's five-game winning streak and reestablished themselves as a Super Bowl contender following a bye week.
Cowboys 49, Giants 17
ARLINGTON, Texas -- Dak Prescott threw for 404 yards and four touchdowns while running for another score, and the Dallas Cowboys routed the New York Giants for the second time this season. The victory extended their home winning streak to 12.
The Cowboys won 40-0 in the opener in New Jersey. The 72-point margin was their largest in a sweep of an NFC East opponent. The previous mark was a 66-point edge against Philadelphia in 1969.
The Giants were outgained 368-27 in the first half with Tommy DeVito at quarterback. He's the first undrafted rookie to start for them at quarterback in the common draft era, save for a strike-replacement game in 1987.
Cardinals 25, Falcons 23
GLENDALE, Ariz. -- Kyler Murray threw for 249 yards and ran for a touchdown in his return from a serious knee injury, Matt Prater made a game-winning 23-yard field goal as time expired and the Arizona Cardinals snapped a six-game losing streak by beating the Atlanta Falcons.
Murray made a pair of important plays on the game-winning drive. The plays provided reminders of why he was the No. 1 overall pick in 2019 and also why the Cardinals signed him to a $230.5 million contract before the 2022 season. Prater made four field goals. The Falcons have lost three straight.
Lions 41, Chargers 38
INGLEWOOD, Calif. -- Jared Goff threw for 333 yards and two touchdowns, Riley Patterson kicked a 41-yard, game-winning field goal as time expired, and the Detroit Lions prevailed in a shootout over the Los Angeles Chargers.
The Chargers tied it at 38-all with 3:34 remaining when Justin Herbert threw his fourth touchdown pass of the day, a 38-yarder to Keenan Allen on fourth-and-1. Goff responded by leading the Lions on a nine-play, 53-yard drive, culminating in Patterson's kick.
Seahawks 29, Commanders 26
SEATTLE -- Jason Myers converted his fifth field goal of the game, a 43-yarder as time expired, and the Seattle Seahawks held off the Washington Commanders.
Seattle quarterback Geno Smith and Washington QB Sam Howell traded big throws and touchdown passes in the final 5 minutes, but it was Smith who had the the final chance at the victory and came through.
Howell pulled Washington even at 26-26 on a 35-yard touchdown pass to Dyami Brown with 52 seconds remaining. Smith took over and made a pair of big throws to DK Metcalf to get the Seahawks into field goal range.
Raiders 16, Jets 12
LAS VEGAS -- Josh Jacobs rushed for 116 yards, rookie Aidan O'Connell connected with Michael Mayer for the game's only touchdown, and the Las Vegas Raiders improved to 2-0 under interim coach Antonio Pierce, beating the New York Jets.
The Raiders turned away two late attempts by the Jets to rally. Robert Spillane intercepted Zach Wilson's pass at the Las Vegas 15 with 1:22 left. After the Raiders punted, Wilson's heave to the end zone fell incomplete on the game's final play.