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Only five NFL teams remain unbeaten and two of them face off in Week 4.
It's an unlikely matchup of 3-0 teams when Patrick Mahomes and the Kansas City Chiefs (-4.5) visit Kirk Cousins and the Las Vegas Raiders on Sunday.
Mahomes and the Chiefs have been here before. It's his fifth 3-0 start in nine seasons. Chiefs, 27-20
Elsewhere:
PITTSBURGH (-2.5) at CLEVELAND: The Steelers finally looked sharp in Mike McCarthy's offense in a 30-27 win against Cincinnati. Deshaun Watson has played excellent football the past two games, especially in the fourth quarter for Cleveland. The Browns are 10-6 on "Thursday Night Football," including 9-1 at home. The Steelers have lost four straight in Cleveland. Browns, 22-20
INDIANAPOLIS (-3.5) vs. WASHINGTON, in London: The Colts ended a nine-game losing streak and now aim to start a winning one. They need Daniel Jones to play better but the defense stepped up last week against Houston. The Commanders stunned the defending Super Bowl champion Seahawks. Colts, 24-18
ARIZONA (-1.5) at NEW YORK GIANTS: The Cardinals have allowed 67 points and lost two in a row since an upset over the Chargers in Week 1. Yet, Arizona is a road favorite in New York. That's because the Giants keep losing key players. Giants, 23-20
DALLAS at HOUSTON (-2.5): The battle of Texas is a matchup between a pair of underachieving teams. The Cowboys bungled one vs. Baltimore in Brazil. Dallas still is having trouble on defense despite new additions and a new coordinator. Houston went 12-2 after an 0-3 start last season. They have no margin for error. Texans, 24-20
GREEN BAY (-3.5) at TAMPA BAY: Jordan Love and the Packers were booed at Lambeau Field during an embarrassing loss to Atlanta. They may have more fans in Tampa Bay where the Cheeseheads could outnumber a hometown crowd that's tired of watching their team lose. BEST BET: Packers, 24-13
JACKSONVILLE at CINCINNATI (-2.5): Trevor Lawrence has been excellent in Jacksonville's wins and the Jaguars have allowed the fewest points in the league. Travis Hunter got his first career pick last week. Maybe this week he gets a chance to make an impact on offense. Joe Burrow leads a potent offense for the Bengals but the revamped defense took a step backward last week. UPSET SPECIAL: Jaguars, 26-24
LOS ANGELES RAMS (-3) at PHILADELPHIA: A questionable pass interference call cost the Rams a win in Denver and the league's best team on paper has a losing record through three games. But the Eagles struggled against third-string QB Case Keenum and have a short week following a Monday night loss. Rams, 26-20
NEW ENGLAND at BUFFALO (-6.5): The Patriots suddenly have a Drake Maye problem. The NFL MVP runner-up has struggled in the first three games after a rough postseason. Josh Allen and the Bills overcame five turnovers to beat the Chargers. Bills, 23-17
NEW YORK JETS at CHICAGO (-3.5): The Jets are playing better, staying competitive and Geno Smith has put his turnover troubles from last season behind. Keenum earned the right to start another one after a masterful performance against the Eagles. Bears, 24-17
TENNESSEE at BALTIMORE (-11.5): The Titans have improved on defense under coach Robert Saleh. But they still haven't won a game. Derrick Henry faces his former team. Ravens, 26-17
MIAMI at MINNESOTA (-10.5): Things were bleak for the Dolphins before they lost their best offensive player, De'Von Achane, for the season. The Vikings are winning games despite an inconsistent offense. Vikings, 23-13
DENVER at SAN FRANCISCO (-2.5): Bo Nix and the Broncos know how to come back. They need a complete game to beat the 49ers. Broncos, 23-22
LOS ANGELES CHARGERS at SEATTLE (-3): The Chargers were supposed to be contenders. But the offense is struggling and they have to find a way to upset Seattle to avoid 0-4. Seahawks, 23-21
DETROIT (-3) at CAROLINA: Detroit's prolific offense is averaging 31 points per game, but the defense is giving up a league-worst 31.7. Jared Goff will face a depleted defense that likely won't have its starting cornerbacks. That's bad news for Carolina. Bryce Young and the Panthers have to win a shootout. Lions, 31-26
ATLANTA at NEW ORLEANS (-2.5): Michael Penix Jr. came back, Bijan Robinson had a big game vs. Green Bay and the Falcons got on the winning track in the first of three straight primetime games. Giving the ball to Robinson is a winning formula for Atlanta. The Saints are 27th against the run. Tyler Shough has eight TD passes but six turnovers for New Orleans, which was competitive in both losses. Saints, 24-23
Last week: Straight up: 9-7. Against spread: 7-8-1.
Overall: Straight up: 29-19. Against spread: 20-27-1.
Best Bet: Straight up: 2-1. Against spread: 1-2.
Upset Special: Straight up: 1-2. Against spread: 2-1.