The Associated Press The Cardinals’ Emari Demercado reacts after fumbling the ball out of the end zone on a possible TD run.

Titans 22, Cardinals 21

GLENDALE, Ariz. — Cam Ward threw for a career-high 265 yards, Joey Slye made a 29-yard field goal as time expired and the Tennessee Titans snapped a 10-game skid with an improbable fourth-quarter comeback, beating the mistake-prone Arizona Cardinals.

The Titans (1-4) trailed 21-6 in the fourth quarter, but took advantage of two massive Cardinals blunders to win the game.

Emari Demercado looked as if he ran for a game-sealing 72-yard touchdown with 12:51 left, but the running back dropped the ball in celebration just before he ran into the end zone. Instead of giving the Cardinals a 28-6 lead, it was ruled a fumble out the back of the end zone, giving the Titans possession at their 20.

Tennessee took advantage of the blunder, driving 80 yards for its first touchdown in eight quarters. Calvin Ridley caught a pass for 47 yards during the scoring drive, which was capped by Tony Pollard’s 1-yard touchdown run, making it 21-12.

Arizona (2-3) made another huge miscue later when Dadrion Taylor-Demerson intercepted Ward’s pass but immediately fumbled. Titans receiver Tyler Lockett fell on the ball in the end zone, cutting the Cardinals lead to 21-19 with 4:51 left.

Vikings 21, Browns 17

LONDON — Vikings receiver Jordan Addison caught a 12-yard touchdown pass from Carson Wentz with 25 seconds left to give Minnesota a victory over Cleveland at Tottenham Hotspur Stadium.

The 10-play, 80-yard drive gave the Vikings (3-2) a much-needed win on their historic international road trip, which started with a 24-21 loss to the Steelers in Dublin last week.

The Vikings improved to 5-0 all time in London.

It also spoiled Dillon Gabriel’s first NFL start, as the Browns rookie put his team (1-4) in position to win by throwing two touchdown passes. Fellow rookie Quinshon Judkins rushed for 110 yards on 23 carries.

Colts 40, Raiders 6

INDIANAPOLIS — Jonathan Taylor ran for three touchdowns and a 2-point conversion, and Daniel Jones threw two touchdown passes as Indianapolis routed Las Vegas.

The 34-point margin was Indy’s largest since it won 37-3 at Jacksonville in 2013.

Jones finished 20 of 29 for 212 yards and moved to 4-1 as a starter this year, surpassing his combined victory total over the past two seasons with the New York Giants. Taylor rushed 17 times for 66 yards and caught three passes for 20 yards — ending a streak of nine straight games with 95 yards or more from scrimmage.

The Colts (4-1) took full advantage of the Raiders’ miscues. They converted a blocked punt, two interceptions and a turnover on downs into TDs.

Cowboys 37, Jets 22

EAST RUTHERFORD, N.J. — Dak Prescott threw two of his four touchdown passes to Jake Ferguson, Dallas scored on two 90-yard drives in the second quarter with a makeshift offensive line missing four starters and the Cowboys rolled past winless New York.

Javonte Williams ran for 135 yards and a touchdown and also caught a TD pass, George Pickens also had a TD reception and the Cowboys (2-2-1) bounced back from a disappointing 40-40 tie against Green Bay last week.

Prescott finished 18 of 29 for 237 yards behind a line that had left guard Tyler Smith (knee), left tackle Tyler Guyton (concussion), right guard Tyler Booker (ankle) and center Cooper Beebe (foot) all out. Right tackle Terence Steele was the only regular starter playing.

Saints 26, Giants 14

NEW ORLEANS — Spencer Rattler passed for an 87-yard touchdown to Rashid Shaheed, safety Jordan Howden returned a fumble 86 yards for a score, and New Orleans defeated turnover-prone New York for the Saints’ first victory under rookie coach Kellen Moore.

Rattler earned his first victory in 11 career starts, passing for 225 yards without a turnover, while Shaheed finished with four catches for 114 yards.

Panthers 27, Dolphins 24

CHARLOTTE. N.C. — Bryce Young threw a go-ahead, 4-yard touchdown pass to Mitchell Evans with 1:59 remaining, Rico Dowdle ran for 206 yards and a score, and Carolina overcame a 17-point first-half deficit to beat Miami.

Young completed 19 of 30 passes for 198 yards and two touchdowns after turning the ball over on Carolina’s first two possessions, leading to two touchdown passes by Tua Tagovailoa and a 17-0 Miami lead.

Making his first start for the Panthers, Dowdle matched the second-highest rushing total in franchise history.

Buccaneers 38, Seahawks 35

SEATTLE — Lavonte David intercepted Sam Darnold with 58 seconds left and Chase McLaughlin kicked a 39-yard field goal as time expired to give Tampa Bay a thrilling win over Seattle.

Baker Mayfield tied it for the Bucs (4-1) by throwing an 11-yard touchdown pass to Sterling Shepard with 1:08 left, and the Seahawks (3-2) took over with the chance to drive for the winning score.

After a short completion to Cooper Kupp, Darnold was intercepted while throwing off his back foot and toward the middle of the field. His pass deflected off defensive end Logan Hall’s helmet and into David’s hands.

Commanders 27, Chargers 10

INGLEWOOD, Calif. — Jacory Croskey-Merritt scored two touchdowns, and Washington rallied from a 10-point deficit after forcing a big fumble in the second quarter to score 27 straight points and beat Los Angeles.

Washington’s Jayden Daniels was 15 of 26 for 231 yards and a touchdown in the game’s final minute in helping the Commanders (3-2) win for the first time on the road after missing two games with an injured left knee.

Lions 37, Bengals 24

CINCINNATI — David Montgomery ran for a touchdown and threw for one on a trick play in his hometown, Jared Goff passed for three scores and the Detroit Lions rolled to their fourth straight win, over the reeling Cincinnati.

Montgomery, a seven-year veteran, had passing and rushing scores in a game for the second time. The bruising rusher played quarterback at Cincinnati Mt. Healthy High School.

Patriots 23, Bills 20

ORCHARD PARK, N.Y. — Drake Maye led the Patriots on a 37-yard drive to set up Andy Borregales’ 52-yard field goal with 15 seconds left, and New England beat the Buffalo Bills on Sunday night, leaving the NFL without an undefeated team five weeks into the season.