Smoke rises after a strike in Tehran, Iran, on Sunday. The U.S. and Israel pounded targets across Iran on Sunday as part of an intensifying military campaign following the killing of Supreme Leader Ayatollah Ali Khamenei. The Associated Press

The U.S. and Israel pounded targets across Iran on Sunday, dropping massive bombs on the country’s ballistic missile sites and wiping out warships as part of an intensifying military campaign following the killing of Supreme Leader Ayatollah Ali Khamenei.

Blasts rattled windows across the country and sent plumes of smoke high into the sky above Tehran. More than 200 people have been killed since the start of the strikes that killed Khamenei and other senior leaders, Iranian leaders have said.

Iran vowed revenge, firing missiles at Israel and Gulf Arab states in a counter­offensive that the U.S. military said resulted in the deaths of three service members — the first known American casualties from the conflict. Israeli rescue services said strikes had hit several locations, including Jerusalem and a synagogue in the central town of Beit Shemesh, where nine people were killed and 28 wounded, bringing the overall death toll in the country to 11. Eleven people were still missing after the strike, police said.

But the attacks on Iran showed no signs of relenting as the U.S. and Israel took aim at key military, political and intelligence targets in what appeared to be a widening war that carried the potential for a prolonged conflict that could envelop the Middle East and destabilize it. The strikes represented a startling show of military might for an American president who swept into office on an “America First” platform and pledged to keep out of “forever wars.”

Trump vows vengeance for deaths

U.S. President Donald Trump said in a video posted to social media that the U.S. would “avenge” the deaths of the service members and that “there will likely be more” killed before the conflict ends.

Israel, which had pledged “nonstop” strikes, said it was increasing its attacks, with 100 fighter jets simultaneously striking targets in Tehran, Brig. Gen. Effie Defrin told reporters at a briefing. The targets included buildings belonging to Iran’s air force, its missile command and its internal security force, which violently quashed anti-government protests in January.

The U.S. military, meanwhile, said B-2 stealth bombers struck Iran’s ballistic missile facilities with 2,000-pound bombs. Trump said on social media that nine Iranian warships had been sunk and that the Iranian navy’s headquarters had been “largely destroyed.”

Europe has mostly stayed out of the war and pressed for diplomacy, but in an indication that the conflict could draw in other nations, Britain, France and Germany said Sunday they were ready to work with the U.S. to help stop Iran’s attacks.

Prime Minister Keir Starmer said Britain would allow the United States to use its bases to strike Iranian missile sites. The U.K. maintains nearby bases on Cyprus and Chagos Islands, a British archipelago in the Indian Ocean.

The weekend attacks were the second time in eight months that the U.S. and Israel had combined against Iran. In the 12-day war last June, Israeli and American strikes greatly weakened Iran’s air defenses, military leadership and nuclear program. But the killing of Khamenei, who ruled Iran for more than three decades, creates a leadership vacuum, increasing the risk of regional instability.

Trump, who a day earlier had encouraged Iranians to “take over” their government, signaled Sunday that he was open to dialogue with Iran’s new leadership.

“They want to talk, and I have agreed to talk, so I will be talking to them,” he told The Atlantic.

Iranian strikes

In the Gulf, Iran’s retaliatory strikes went beyond U.S. and Israeli targets, pushing the conflict into cities that have long marketed themselves as regional safe havens.

The foreign ministers of Qatar, Saudi Arabia, the United Arab Emirates, Kuwait, Oman and Bahrain said Sunday that their countries retain “the legal right to respond and the right to self-defense” after Iranian strikes hit hotels, airports and other sites in multiple cities throughout the Gulf.

In the United Arab Emirates, authorities said most Iranian missiles and drones were intercepted. But some either got through or fell as debris, killing three people, injuring others and causing significant damage.

Bahrain and Kuwait said Iranian strikes in both countries hit civilian targets.

Streets of Tehran largely deserted

In Tehran, there was little sign that Iranians had heeded Trump’s call for an uprising against the government.

The streets were largely deserted as people sheltered during airstrikes, witnesses told The Associated Press, speaking anonymously for fear of retribution. The paramilitary Basij, which has played a central role in crushing protests, set up checkpoints across the city, they said.

Two powerful explosions were heard in Tehran’s Niavaran neighborhood late Sunday.

An eyewitness in the city told AP that the windows of their apartment shook violently, and residents came out onto the streets fearing it was too dangerous to stay inside. The witness spoke on condition of anonymity for fear of reprisals. Video footage from Tehran showed plumes of smoke filling the skyline, and the official IRNA news agency reported that parts of the building of the Islamic Republic of Iran Broadcasting (IRIB) were struck Sunday.

In southern Iran, at least 165 people were killed Saturday when a girls’ school was struck, and dozens more were wounded, IRNA reported. The Israeli military said it was not aware of strikes in the area. The U.S. military said it was looking into the reports.

New Iranian leadership in place

Iranian President Masoud Pezeshkian said in a prerecorded message that a new leadership council had begun its work. The country’s foreign minister, Abbas Araghchi, said a new supreme leader would be chosen in “one or two days.”