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FDA proposes new system to OK customized drugs for rare diseases

Federal health officials on Monday laid out a proposal to spur development of customized treatments for patients with hard-to-treat diseases, including for rare genetic conditions that the pharmaceutical industry has long considered unprofitable. The preliminary Food and Drug Administration guidelines, if implemented, would create a new pathway for bespoke therapies that have only been tested in a handful of patients due to the challenges of conducting larger studies. The FDA announcement specifically mentions gene editing, although agency officials said the new approach could also be ...

Ticker: Top Court agrees to hear from oil, gas companies

The Supreme Court has agreed to hear from oil and gas companies trying to block lawsuits seeking to hold the industry liable for billions of dollars in damage linked to climate change. The conservative-majority court took up the case Monday. The companies went to the Supreme Court after Colorado’s highest court allowed a lawsuit from Boulder to proceed. Panama orders occupation of key ports Panama has ordered the occupation of two key ports at the ends of the Panama Canal. It comes after its top court ruled that the operator’s contract is unconstitutional. The government on ...

NYC nurses strike ends

NEW YORK — New York City’s largest nursing strike in decades may be on the verge of ending after a union representing more than 4,000 nurses in the NewYork-Presbyterian hospital system reached a tentative contract agreement with management early Friday. The nurses’ union, the New York State Nurses Association, and NewYork-Presbyterian both said their negotiators have reached a tentative deal. The union said provisions include raises topping 12% over three years, staffing improvements and, for the first time, safeguards on the use of artificial intelligence. Union members were ...

Wall Street keeps calm after SCOTUS strikes down tariffs

NEW YORK — Wall Street kept calm Friday after the Supreme Court struck down President Donald Trump’s sweeping tariffs, which had triggered panic in financial markets when announced last year, and stocks ticked higher. The S&P 500 rose 0.7%. It had been flipping between small gains and losses before the court’s ruling, following discouraging reports showing slowing growth for the U.S. economy and faster inflation. The Dow Jones Industrial Average added 230 points, or 0.5%, and the Nasdaq composite rose 0.9%. Many on Wall Street were likely expecting such a ruling from the ...

Administration eases limits on coal plant emissions

WASHINGTON — The Environmental Protection Agency on Friday weakened limits on mercury and other toxic emissions from coal-fired power plants, the Trump administration’s latest effort to boost the fossil fuel industry by paring back clean air and water rules. Toxic emissions from coal- and ...