KABUL, Afghanistan — Afghanistan accused Pakistan of killing at least 400 people in an airstrike on a drug rehabilitation hospital in the Afghan capital late Monday. It marked a dramatic escalation of a conflict that began late last month and has seen repeated cross-border clashes as well as airstrikes inside Afghanistan. International calls for a ceasefire have gone unheeded.

Pakistan dismissed the accusation that it had hit a hospital, saying its strikes, which were also conducted in eastern Afghanistan, did not hit any civilian sites.

Afghanistan’s deputy government spokesperson Hamdullah Fitrat, in a post on X, said the airstrike had hit the hospital in Kabul at about 9 p.m. local time, destroying large sections of the 2,000-bed facility. He said the death toll had “so far” reached 400 people, while about 250 people had been reported injured.

Local television stations posted footage on X showing security forces using flashlights as they carried out casualties while firefighters struggled to extinguish flames among the ruins of a building. Fitrat said rescue teams were working to control the fire and recover the bodies.

The strike came hours after Afghan officials said the two sides exchanged fire along their common border, killing four people in Afghanistan, as the deadliest fighting between the neighbors in years entered a third week.

Afghan government spokesperson Zabihullah Mujahid condemned the strike on X, accusing Pakistan of “targeting hospitals and civilian sites to perpetrate horrors.” In a post before the death toll rose into the hundreds, he said those killed and injured were patients at the hospital.

“We strongly condemn this crime and consider such an act to be against all accepted principles and a crime against humanity,” he posted.

Pakistan dismisses the allegations

Pakistani Prime Minister Shehbaz Sharif’s spokesperson, Mosharraf Zaidi, dismissed the allegations as baseless, saying no hospital was targeted in Kabul.

Pakistan’s Information Minister Attaullah Tarar posted on X in the early hours Tuesday that the Pakistani military had “carried out precision airstrikes” targeting military installations in Kabul and the eastern province of Nangarhar. He said “technical support infrastructure and ammunition storage facilities” at two locations in Kabul were destroyed.

“All targeting has been done with precision only at those infrastructures which are being used by Afghan Taliban regime to support its multiple terror proxies,” he wrote.

Pakistan’s Ministry of Information said earlier that Mujahid’s claim was “false and misleading” and aimed at stirring sentiment and cover what it described as “illegitimate support for cross-border terrorism.” It said Pakistan’s targeting was “precise and carefully undertaken to ensure no collateral damage is inflicted.”

UN calls on Afghanistan to combat militants

The strike came hours after the U.N. Security Council called on Afghanistan’s Taliban rulers to immediately step up efforts to combat terrorism. Pakistan accuses Kabul of harboring militant groups, particularly the Pakistani Taliban, which it says carry out attacks inside Pakistan.

The Security Council resolution, adopted unanimously, didn’t refer specifically to attacks carried out in Pakistan but condemns “in the strongest terms all terrorist activity including terrorist attacks.” The resolution also extends the U.N. political mission in Afghanistan, UNAMA, for three months.